Managing Chemotherapy Side Effects: A Guide for Patients and Caregivers

Undergoing cancer treatment is a challenging journey, but understanding how to manage side effects can make it more manageable. Chemotherapy, immunotherapy, and biotherapy target cancer cells but may also affect healthy cells, leading to various side effects. Here's a comprehensive guide to help you and your caregivers navigate these challenges.

1. Fatigue

Fatigue is a common side effect. To manage it:

  • Prioritize activities when you feel your best.

  • Take short naps and listen to your body.

  • Engage in light activities like walking, yoga, or stretching to boost energy levels.

2. Loss of Appetite

Cancer and chemotherapy can reduce your appetite. Try:

  • Eating small, frequent meals (4–6 times a day).

  • Focusing on high-protein foods and supplementing with protein shakes.

  • Keeping easy-to-digest snacks on hand.

3. Nausea and Vomiting

Nausea is often managed with pre-treatment medications and take-home prescriptions. Tips:

  • Take nausea medications at the first sign of discomfort.

  • If vomiting occurs, contact your care team for further guidance.

4. Diarrhea and Constipation

  • For diarrhea: Follow your care team’s recommendations and use over-the-counter medications like Imodium as directed. Call your clinic if symptoms persist.

  • For constipation: Avoid going more than three days without a bowel movement. Stay hydrated and monitor for abdominal pain or bloating.

5. Dehydration

Stay hydrated to avoid complications:

  • Aim for 8–10 glasses of water a day.

  • Keep water nearby and set hydration reminders.

6. Mouth Sores

Mouth sores or ulcers are common. To care for your mouth:

  • Brush daily with fluoride toothpaste and a soft toothbrush.

  • Avoid alcohol-based mouthwashes; instead, use a homemade rinse with baking soda and salt.

  • Stick to soft, bland foods to reduce discomfort.

7. Hair and Skin Changes

Hair loss or thinning is usually temporary. For skin care:

  • Avoid sun exposure and use SPF 30 sunscreen.

  • Moisturize with hypoallergenic creams and avoid harsh soaps.

  • Report rashes or skin peeling to your care team immediately.

8. Blood Cell Changes

Chemotherapy can reduce your red cells, white cells, and platelets, affecting your oxygen levels, immunity, and clotting ability. Prevent infections by:

  • Washing your hands frequently.

  • Avoiding sick individuals and wearing gloves during housework.

  • Monitoring your temperature and contacting your care team for fevers over 100.4°F.

9. Managing Emergencies

Know when to seek immediate care:

  • Call your clinic if symptoms like severe diarrhea, vomiting, or constipation worsen.

  • Go to the ER for fevers above 101°F or persistent symptoms.

Additional Support

Your oncology team, including doctors, nurses, pharmacists, and dieticians, is there to guide you. Cancer treatment affects everyone differently, so follow your care team’s instructions and reach out for support when needed. With proper symptom management, you can focus on healing and recovery.

For personalized advice, consult your healthcare provider.

About Dr. Sourabh Kharait

Dr. Sourabh Kharait (MD / PhD) is Clinical Nephrologist and Medical Director of Clinical Trials at Summit Nephrology Medical Group, and the Founder and CEO of IGH Naturals, a platform company that designs Functional Foods and Nutritional products for athletes and patients with chronic diseases.


For more information on how HuMOLYTE can support your gut health during chemotherapy, visit our product page or consult your health care provider.

This blog is for educational purposes only and is not intended as medical advice. Always consult with your healthcare provider before making any changes to your treatment plan, hydration strategies, or diet. The information provided here is based on general insights and may not apply to individual circumstances.

Dr. Sourabh Kharait

Dr. Sourabh Kharait (MD / PhD) is Clinical Nephrologist and Medical Director of Clinical Trials at Summit Nephrology Medical Group, and the Founder and CEO of IGH Naturals, a platform company that designs Functional Foods and Nutritional products for athletes and patients with chronic diseases. Dr. Kharait is the inventor of the patented MAGNAK electrolyte formula designed to prevent muscle cramps in athletes as well as HuMOLYTE, an electrolyte mix with human milk oligosaccharides. Dr. Kharait has more than a decade of clinical experience caring of patients with electrolyte and kidney problems and he has led numerous clinical trials for patients in the renal and cardiovascular field. He has authored numerous peer reviewed original research articles, book chapters, expert opinions and has advised numerous professional athletes on hydration and nutritional practice.

https://www.linkedin.com/in/sourabh-kharait-md-phd-94871172/
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